yellow fever |
Disease ID | 966 |
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Disease | yellow fever |
Definition | An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus. The severe form is characterized by fever, HEMOLYTIC JAUNDICE, and renal damage. |
Synonym | [x]yellow fever, unspecified [x]yellow fever, unspecified (disorder) fever, yellow fevers, yellow yellow fever (disorder) yellow fever [disease/finding] yellow fever nos yellow fever unspecified yellow fever unspecified (disorder) yellow fever virus infection yellow fever, nos yellow fever, unspecified yellow fevers yf - yellow fever |
Orphanet | |
DOID | |
ICD10 | |
UMLS | C0043395 |
MeSH | |
SNOMED-CT | |
Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:6) |
Curated Gene | (Waiting for update.) |
Inferring Gene | (Waiting for update.) |
Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:76) 2 | A2M | 1.362 | DISEASES 10195 | ALG3 | 2.494 | DISEASES 250 | ALPP | 2.669 | DISEASES 64115 | C10orf54 | 3.095 | DISEASES 755 | C21orf2 | 4.516 | DISEASES 22900 | CARD8 | 1.83 | DISEASES 79872 | CBLL1 | 2.769 | DISEASES 388372 | CCL4L1 | 1.427 | DISEASES 9560 | CCL4L2 | 1.281 | DISEASES 959 | CD40LG | 4.497 | DISEASES 170482 | CLEC4C | 1.4 | DISEASES 10675 | CSPG5 | 3.435 | DISEASES 4283 | CXCL9 | 1.175 | DISEASES 192668 | CYS1 | 1.65 | DISEASES 147906 | DACT3 | 2.083 | DISEASES 51428 | DDX41 | 1.298 | DISEASES 23586 | DDX58 | 2.189 | DISEASES 23405 | DICER1 | 1.455 | DISEASES 1805 | DPT | 3.383 | DISEASES 29102 | DROSHA | 2.131 | DISEASES 83658 | DYNLRB1 | 1.79 | DISEASES 6993 | DYNLT1 | 1.464 | DISEASES 51386 | EIF3L | 3.809 | DISEASES 1999 | ELF3 | 2.478 | DISEASES 30816 | ERVW-1 | 4.146 | DISEASES 2114 | ETS2 | 1.117 | DISEASES 2213 | FCGR2B | 1.626 | DISEASES 2214 | FCGR3A | 1.353 | DISEASES 51218 | GLRX5 | 2.197 | DISEASES 2813 | GP2 | 1.379 | DISEASES 3062 | HCRTR2 | 2.431 | DISEASES 5654 | HTRA1 | 1.129 | DISEASES 3586 | IL10 | 1.733 | DISEASES 51135 | IRAK4 | 1.402 | DISEASES 3665 | IRF7 | 2.011 | DISEASES 9636 | ISG15 | 1.182 | DISEASES 23210 | JMJD6 | 1.281 | DISEASES 3916 | LAMP1 | 1.568 | DISEASES 389421 | LIN28B | 1.407 | DISEASES 497634 | LINC00293 | 4.114 | DISEASES 100885779 | LINC-ROR | 1.102 | DISEASES 116511 | MAS1L | 2.672 | DISEASES 284424 | MIR7-3HG | 1.817 | DISEASES 4512 | MT-CO1 | 2.727 | DISEASES 4513 | MT-CO2 | 1.242 | DISEASES 4538 | MT-ND4 | 1.954 | DISEASES 4540 | MT-ND5 | 1.248 | DISEASES 4615 | MYD88 | 1.016 | DISEASES 23218 | NBEAL2 | 1.437 | DISEASES 4700 | NDUFA6 | 2.079 | DISEASES 246734 | NPCDR1 | 1.128 | DISEASES 4923 | NTSR1 | 1.025 | DISEASES 4938 | OAS1 | 1.641 | DISEASES 4939 | OAS2 | 3.017 | DISEASES 8398 | PLA2G6 | 1.103 | DISEASES 5454 | POU3F2 | 1.65 | DISEASES 5478 | PPIA | 2.457 | DISEASES 149830 | PRNT | 5.597 | DISEASES 5625 | PRODH | 1.378 | DISEASES 6050 | RNH1 | 1.353 | DISEASES 6161 | RPL32 | 2.307 | DISEASES 6175 | RPLP0 | 1.864 | DISEASES 6176 | RPLP1 | 2.819 | DISEASES 6181 | RPLP2 | 1.849 | DISEASES 6235 | RPS29 | 2.727 | DISEASES 23212 | RRS1 | 1.139 | DISEASES 91543 | RSAD2 | 2.027 | DISEASES 123228 | SENP8 | 5.832 | DISEASES 6614 | SIGLEC1 | 1.612 | DISEASES 11005 | SPINK5 | 1.175 | DISEASES 6996 | TDG | 1.722 | DISEASES 51284 | TLR7 | 2.56 | DISEASES 54106 | TLR9 | 2.311 | DISEASES 7124 | TNF | 2.282 | DISEASES 8718 | TNFRSF25 | 1.407 | DISEASES 11169 | WDHD1 | 2.048 | DISEASES |
Locus | (Waiting for update.) |
Disease ID | 966 |
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Disease | yellow fever |
Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:29) HP:0002239 | Gastrointestinal hemorrhage HP:0002027 | Abdominal pain HP:0400008 | Menometrorrhagia HP:0001287 | Meningitis HP:0002383 | Encephalitis HP:0000093 | Proteinuria HP:0000083 | Renal insufficiency HP:0001635 | Congestive heart failure HP:0002829 | Arthralgia HP:0006554 | Acute hepatic failure HP:0003326 | Myalgia HP:0001254 | Lethargy HP:0002014 | Diarrhea HP:0100520 | Oliguria HP:0002615 | Hypotension HP:0000112 | Nephropathy HP:0002017 | Nausea and vomiting HP:0001944 | Dehydration HP:0000952 | Jaundice HP:0005268 | Spontaneous abortion HP:0011675 | Arrhythmia HP:0001945 | Fever HP:0002045 | Hypothermia HP:0000613 | Photophobia HP:0100749 | Chest pain HP:0006543 | Cardiorespiratory arrest HP:0002039 | Anorexia HP:0002315 | Headache HP:0002047 | Malignant hyperthermia |
Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:1) |
Disease ID | 966 |
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Disease | yellow fever |
Manually Symptom | UMLS | Name(Total Manually Symptoms:2) |
Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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(Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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(Waiting for update.) |
All Snps(Total Genotypes:0) | |
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(Waiting for update.) |
GWASdb Annotation(Total Genotypes:0) | |
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(Waiting for update.) |
GWASdb Snp Trait(Total Genotypes:0) | |
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(Waiting for update.) |
Mapped by lexical matching(Total Items:6) | ||||
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HP ID | HP Name | MP ID | MP Name | Annotation |
HP:0002239 | Gastrointestinal hemorrhage | MP:0012305 | umbilical cord hemorrhage | bleeding into or from the umbilical cord |
HP:0006554 | Acute hepatic failure | MP:0002628 | hepatic steatosis | an accumulation of fat deposits in the liver |
HP:0000083 | Renal insufficiency | MP:0003335 | exocrine pancreatic insufficiency | inadequate synthesis and/or secretion of digestive enzymes by the exocrine portion of the pancreas, usually due to loss of acinar tissue from idiopathic atrophy or acute or chronic inflammation, causing maldigestion and malabsorption of nutrients |
HP:0002017 | Nausea and vomiting | MP:0010426 | abnormal heart and great artery attachment | any anomaly in the in the position or pattern of the connection site of the heart to any of the great arteries, including the pulmonary artery and aorta |
HP:0002047 | Malignant hyperthermia | MP:0020214 | susceptible to malignant hyperthermia | increased susceptibility to hyperthermia triggered by exposure to certain drugs used for general anesthesia, specifically the volatile anesthetic agents and the neuromuscular blocking agent, succinylcholine |
HP:0001635 | Congestive heart failure | MP:0011925 | abnormal heart echocardiography feature | any anomaly in echocardiographic representation of systolic and diastolic function, ventricular compliance, valvular function, or interventricular septum features |
Mapped by homologous gene(Total Items:27) | ||||
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HP ID | HP Name | MP ID | MP Name | Annotation |
HP:0001945 | Fever | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
HP:0006554 | Acute hepatic failure | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
HP:0011675 | Arrhythmia | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
HP:0001944 | Dehydration | MP:0014206 | decreased intestinal epithelial sodium ion transmembrane transport | |
HP:0002315 | Headache | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
HP:0000112 | Nephropathy | MP:0020234 | decreased basal metabolism | decrease in heat production of an organism at the lowest level of cell chemistry in an inactive, awake, and fasting state |
HP:0001287 | Meningitis | MP:0020215 | impaired blood coagulation | impaired ability of the blood to clot |
HP:0000093 | Proteinuria | MP:0020216 | decreased circulating complement protein level | less than normal levels of the serum proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes |
HP:0002239 | Gastrointestinal hemorrhage | MP:0020215 | impaired blood coagulation | impaired ability of the blood to clot |
HP:0002014 | Diarrhea | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
HP:0002017 | Nausea and vomiting | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
HP:0002039 | Anorexia | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
HP:0000952 | Jaundice | MP:0020215 | impaired blood coagulation | impaired ability of the blood to clot |
HP:0002383 | Encephalitis | MP:0020215 | impaired blood coagulation | impaired ability of the blood to clot |
HP:0002829 | Arthralgia | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
HP:0002045 | Hypothermia | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
HP:0000083 | Renal insufficiency | MP:0020316 | decreased vascular endothelial cell proliferation | decrease in the expansion rate of any vascular endothelial cell population by cell division |
HP:0002027 | Abdominal pain | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
HP:0001254 | Lethargy | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
HP:0003326 | Myalgia | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
HP:0001635 | Congestive heart failure | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
HP:0000613 | Photophobia | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
HP:0100749 | Chest pain | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
HP:0002615 | Hypotension | MP:0020214 | susceptible to malignant hyperthermia | increased susceptibility to hyperthermia triggered by exposure to certain drugs used for general anesthesia, specifically the volatile anesthetic agents and the neuromuscular blocking agent, succinylcholine |
HP:0006543 | Cardiorespiratory arrest | MP:0011100 | preweaning lethality, complete penetrance | death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age) |
HP:0002047 | Malignant hyperthermia | MP:0020214 | susceptible to malignant hyperthermia | increased susceptibility to hyperthermia triggered by exposure to certain drugs used for general anesthesia, specifically the volatile anesthetic agents and the neuromuscular blocking agent, succinylcholine |
HP:0005268 | Spontaneous abortion | MP:0020040 | decreased bone ossification | decrease in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance |
Disease ID | 966 |
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Disease | yellow fever |
Case | (Waiting for update.) |